产品货号：
Z16823
中文名称：
GOLPH3抗体
英文名称：
Anti-GOLPH3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GOLPH3 Antibody |
| 指标别名 | Coat protein GPP34;Golgi phosphoprotein 3;GOLPH3;GOPP1;GPP34;MIDAS |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IF |
| 基因名称 | GOLPH3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | GOLPH3 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human GOLPH3.The immunogen is located within the first 50 amino acids of GOLPH3. |
| 计算分子量 | 34kDa |
| 成分 | GOLPH3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | GOLPH3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | GOLPH3 was initially identified as a peripheral membrane protein localized to the trans-Golgi network,but others reported it to be primarily a mitochondrial protein that regulated the mitochondrial mass through the regulation of the mitochondria-specific phospholipid cardiolipin.GOLPH3 has since been implicated in the target of rapamycin (TOR) signalling pathway.Its overexpression in transfected cells led to and increase in anchorage-independent growth and cell proliferation in vitro.Furthermore,GOLPH3-transfected cells enhanced S6 Kinase activity in response to growth factor stimulation by EGF.Simultaneously,AKT phosphorylation increased in these cells,while these events were abrogated in GOLPH3 siRNA treated cells compared to control cells,indicating the GOLPH3 can enhance signalling through TOR-associated complexes.These results suggest that GOLPH3 is a bona fide oncogene and may be a useful target for therapeutic strategies. |
| Uniprot ID | Q9H4A6 |
| 基因名全称 | Golgi phosphoprotein 3 (coat-protein) |
| 蛋白名全称 | Golgi phosphoprotein 3 (coat-protein) |
| 推荐稀释比 | GOLPH3 antibody can be used for detection of GOLPH3 by Western blot at 0.5 ～ 1μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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